QuantiFERON-TB Gold One blood test, one clear answer for the diagnosis of Mycobacterium tuberculosis infection. > More details
	QuantiFERON-TB Gold In-Tube Tuberculosis testing doesn't get any easier or better. > More details
	QuantiFERON-CMI Test for the measurement of cell mediated immune responses in humans using whole blood. > More details
	QuantiFERON-CMV Research test for measuring T-c   QuantiFERON-CMV ell responses to CMV. > More details

Quantiferon Technology

QuantiFERONTechnology is a unique approach to disease detection and monitoring. As the only in-vitro diagnostic technology available to provide information on the activity of the cell-mediated functions of the immune system from whole blood samples, QuantiFERONopens doors to new understanding of important diseases and to new approaches in disease detection, management and control.

Individuals exposed to diseases have specific T cell lymphocytes in their blood that maintain an immunological memory for the immunologically reactive molecules (antigens) of  the priming disease, be that an infectious disease or a cancer cell.   The addition of a disease antigen  to blood collected from a primed individual results in the rapid re-stimulation of antigen-specific effector T cells, resulting in the release of the cytokine Interferon-gamma (IFN-).  Effector T cells are able to respond quickly when exposed to the priming antigen. Thus the production of IFN- in response to antigen exposure is a specific marker for cellular immune response against that disease antigen (recall response).

This is illustrated in the following diagram:

 
  
 
The stimulation of effector T cells in whole blood with a specific antigen(s) or mitogen, and the subsequent simple quantification of the resulting IFN- in the plasma, is the basis of the QuantiFERON technology.

למידע בעברית על קואנטיפרון לאבחון שחפת

Quantiferon Medical and Scientific publications

QFT Publications (alphabetical listing)

Sensitivity and Specificity in Active TB

Diagnosing Latent TB infection (LTBI) in Contacts

TB Testing Guidelines related to QFT

QFT Cost Effectiveness Data

Position Statements and Editorials on Interferon-gamma tests

Reviews on Interferon-gamma tests for detection of TB

Performance in the clinically ill

Performance of QFT in Children

Diagnosing Latent TB infection (LTBI) in the Immune-suppressed

Diagnosing Latent TB infection (LTBI) in Screening Programs